A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection.

To investigate the pathogenesis of Legionnaires disease at a molecular level, we mutated by directed allelic exchange a gene encoding a Legionella pneumophila-specific 24,000-dalton (Da) surface protein. Southern hybridization and immunoblot analyses demonstrated that the predicted DNA rearrangement...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Cianciotto, N P, Eisenstein, B I, Mody, C H, Toews, G B, Engleberg, N C
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1989
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2925251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.4.1255-1262.1989
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