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A detailed characterization of the adult mouse model of glycogen storage disease Ia

Glycogen storage disease type Ia (GSDIa) is caused by a genetic defect in the hepatic enzyme glucose-6-phosphatase (G6Pase-α), which manifests as life-threatening hypoglycemia with related metabolic complications. A G6Pase-α knockout (KO) mouse model was generated to study potential therapies for co...

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Detalhes bibliográficos
Main Authors: Salganik, Susan V, Weinstein, David A, Shupe, Thomas D, Salganik, Max, Pintilie, Dana G, Petersen, Bryon E
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132560/
https://ncbi.nlm.nih.gov/pubmed/19581879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.64
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