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The aneuploidy paradox in cell growth and tumorigenesis
Aneuploidy, an abnormal chromosome number, is a frequent characteristic of malignant cells, leading to the suggestion that aneuploidy drives tumorigenesis. In a recent issue of Science, Williams et al. demonstrated that chromosome gains in primary cells cause proliferative defects, which is paradoxi...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132552/ https://ncbi.nlm.nih.gov/pubmed/19061834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.11.011 |
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