Modulation of the immune response to pneumococcal type 14 capsular polysaccharide-protein conjugates by the adjuvant Quil A depends on the properties of the conjugates.

Streptococcus pneumoniae type 14 capsular polysaccharide-bovine serum albumin (S14PS-BSA) conjugates were prepared by water-soluble-carbodiimide-mediated condensation with or without the use of N-hydroxy-sulfosuccinimide. The immunogenicities of the capsular polysaccharide (S14PS) and of the conjuga...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Verheul, A F, Versteeg, A A, De Reuver, M J, Jansze, M, Snippe, H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313232/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2925240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.4.1078-1083.1989
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