Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: a case-control study

INTRODUCTION: Systemic sclerosis (SSc) complicated by pulmonary arterial hypertension (PAH) carries a poor prognosis, despite pulmonary vascular dilating therapy. Platelet-derived growth factor receptor-β (PDGFR-β) and epidermal growth factor receptor (EGFR) are potential therapeutic targets for PAH...

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Detalhes bibliográficos
Main Authors: Overbeek, Maria J, Boonstra, Anco, Voskuyl, Alexandre E, Vonk, Madelon C, Vonk-Noordegraaf, Anton, van Berkel, Maria PA, Mooi, Wolter J, Dijkmans, Ben AC, Hondema, Laurens S, Smit, Egbert F, Grünberg, Katrien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132056/
https://ncbi.nlm.nih.gov/pubmed/21492463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3315
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