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Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death
Mitotic death is a major form of cell death in cancer cells that have been treated with chemotherapeutic drugs. However, the mechanisms underlying this form of cell death is poorly understood. Here, we report that the loss of chromosome integrity is an important determinant of mitotic death. During...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131938/ https://ncbi.nlm.nih.gov/pubmed/21151026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.165 |
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