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Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action

Identifying the molecular mechanisms responsible for the resistance of gliomas to anticancer treatments is an issue of great therapeutic interest. Δ(9)-Tetrahydrocannabinol (THC), the major active ingredient of marijuana, and other cannabinoids inhibit tumor growth in animal models of cancer, includ...

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Detalhes bibliográficos
Main Authors: Lorente, M, Torres, S, Salazar, M, Carracedo, A, Hernández-Tiedra, S, Rodríguez-Fornés, F, García-Taboada, E, Meléndez, B, Mollejo, M, Campos-Martín, Y, Lakatosh, S A, Barcia, J, Guzmán, M, Velasco, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131933/
https://ncbi.nlm.nih.gov/pubmed/21233844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.170
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