HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

The apoptotic effect of oxidized LDLs (oxLDLs) is mediated through a complex sequence of signaling events involving a deregulation of the cytosolic Ca(2+) homeostasis. OxLDLs also trigger ER stress that may lead to cellular dysfunction and apoptosis, through the activation of the IRE1α/c-Jun N-termi...

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Bibliographic Details
Main Authors: Muller, C, Salvayre, R, Nègre-Salvayre, A, Vindis, C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131925/
https://ncbi.nlm.nih.gov/pubmed/21113143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.149
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