Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells

L-glutamate, the major excitatory neurotransmitter, also has a role in non-neuronal tissues and modulates immune responses. Whether NMDA receptor (NMDAR) signalling is involved in T-cell development is unknown. In this study, we show that mouse thymocytes expressed an array of glutamate receptors, i...

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Detalhes bibliográficos
Main Authors: Affaticati, P, Mignen, O, Jambou, F, Potier, M-C, Klingel-Schmitt, I, Degrouard, J, Peineau, S, Gouadon, E, Collingridge, G L, Liblau, R, Capiod, T, Cohen-Kaminsky, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131881/
https://ncbi.nlm.nih.gov/pubmed/20577261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.79
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