Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages.

To determine whether extracellular tryptophan degradation represents an oxygen-independent antimicrobial mechanism, we examined the effect of exogenous tryptophan on the intracellular antimicrobial activity of gamma interferon (IFN-gamma)-stimulated human macrophages. IFN-gamma readily induced norma...

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Publicat a:Infect Immun
Autors principals: Murray, H W, Szuro-Sudol, A, Wellner, D, Oca, M J, Granger, A M, Libby, D M, Rothermel, C D, Rubin, B Y
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1989
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2492973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.3.845-849.1989
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