A carregar...
Design, Synthesis, Biological Evaluation, and Structure–Activity Relationships of Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl)benzenesulfonates as New Tubulin Inhibitors Mimicking Combretastatin A-4
[Image: see text] Sixty-one phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates (PIB-SOs) and 13 of their tetrahydro-2-oxopyrimidin-1(2H)-yl analogues (PPB-SOs) were prepared and biologically evaluated. The antiproliferative activities of PIB-SOs on 16 cancer cell lines are in the nanomolar range and...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131785/ https://ncbi.nlm.nih.gov/pubmed/21604746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200488a |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|