Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling

AIMS/HYPOTHESIS: The adiponectin signalling pathway is largely unknown, but recently the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1), has been shown to interact directly with adiponectin receptor (ADIPOR)1. APPL1 is present i...

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Detalhes bibliográficos
Main Authors: Holmes, R. M., Yi, Z., De Filippis, E., Berria, R., Shahani, S., Sathyanarayana, P., Sherman, V., Fujiwara, K., Meyer, C., Christ-Roberts, C., Hwang, H., Finlayson, J., Dong, L. Q., Mandarino, L. J., Bajaj, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131511/
https://ncbi.nlm.nih.gov/pubmed/21562756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2173-x
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