Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice

AIMS/HYPOTHESIS: Obesity is strongly associated with the development of non-alcoholic fatty liver disease (NAFLD). The cytokine osteopontin (OPN) was recently shown to be involved in obesity-induced adipose tissue inflammation and reduced insulin response. Accumulating evidence links OPN to the path...

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Detalhes bibliográficos
Main Authors: Kiefer, F. W., Neschen, S., Pfau, B., Legerer, B., Neuhofer, A., Kahle, M., Hrabé de Angelis, M., Schlederer, M., Mair, M., Kenner, L., Plutzky, J., Zeyda, M., Stulnig, T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131508/
https://ncbi.nlm.nih.gov/pubmed/21562757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2170-0
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