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Intratumoral Drug Delivery with Nanoparticulate Carriers

Stiff extracellular matrix, elevated interstitial fluid pressure, and the affinity for the tumor cells in the peripheral region of a solid tumor mass have long been recognized as significant barriers to diffusion of small-molecular-weight drugs and antibodies. However, their impacts on nanoparticle-...

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Detalhes bibliográficos
Main Authors: Holback, Hillary, Yeo, Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131473/
https://ncbi.nlm.nih.gov/pubmed/21213021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0360-y
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