Circulating activated and effector memory T cells are associated with calcification and clonal expansions in bicuspid and tricuspid valves of calcific aortic stenosis*

We sought to delineate further the immunological significance of T lymphocytes infiltrating the valve leaflets in calcific aortic stenosis (CAS) and determine whether there were associated alterations in circulating T cells. Using clonotypic TCR β-chain length and sequence analysis we confirmed the...

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Detalhes bibliográficos
Principais autores: Winchester, Robert, Wiesendanger, Margrit, O’Brien, Will, Zhang, Hui-Zhu, Maurer, Mathew S., Gillam, Linda D., Schwartz, Allan, Marboe, Charles, Stewart, Allan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131440/
https://ncbi.nlm.nih.gov/pubmed/21677140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003521
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