An epigenetic marker panel for detection of lung cancer using cell-free serum DNA

PURPOSE: We investigated the feasibility of detecting aberrant DNA methylation of some novel and known genes in the serum of lung cancer patients. EXPERIMENTAL DESIGN: To determine the analytical sensitivity, we examined the tumor and the matched serum DNA for aberrant methylation of fifteen gene pr...

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Main Authors: Begum, Shahnaz, Brait, Mariana, Dasgupta, Santanu, Ostrow, Kimberly, Zahurak, Marianna, Carvalho, André L., Califano, Joseph A., Goodman, Steven N., Westra, William H., Hoque, Mohammad Obaidul, Sidransky, David
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131425/
https://ncbi.nlm.nih.gov/pubmed/21610147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3436
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