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Nucleotide excision repair in rat male germ cells: low level of repair in intact cells contrasts with high dual incision activity in vitro

The acquisition of genotoxin-induced mutations in the mammalian germline is detrimental to the stable transfer of genomic information. In somatic cells, nucleotide excision repair (NER) is a major pathway to counteract the mutagenic effects of DNA damage. Two NER subpathways have been identified, gl...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Jansen, Jacob, Olsen, Ann Karin, Wiger, Richard, Naegeli, Hanspeter, de Boer, Peter, van der Hoeven, Frits, Holme, Jørn Andreas, Brunborg, Gunnar, Mullenders, Leon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292852/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.8.1791
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