TBP Binding-Induced Folding of the Glucocorticoid Receptor AF1 Domain Facilitates Its Interaction with Steroid Receptor Coactivator-1

The precise mechanism by which glucocorticoid receptor (GR) regulates the transcription of its target genes is largely unknown. This is, in part, due to the lack of structural and functional information about GR's N-terminal activation function domain, AF1. Like many steroid hormone receptors (...

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Hlavní autoři: Khan, Shagufta H., Ling, Jun, Kumar, Raj
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131385/
https://ncbi.nlm.nih.gov/pubmed/21760925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021939
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