Modeling and automation of sequencing-based characterization of RNA structure

Sequence census methods reduce molecular measurements such as transcript abundance and protein-nucleic acid interactions to counting problems via DNA sequencing. We focus on a novel assay utilizing this approach, called selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-S...

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Main Authors: Aviran, Sharon, Trapnell, Cole, Lucks, Julius B., Mortimer, Stefanie A., Luo, Shujun, Schroth, Gary P., Doudna, Jennifer A., Arkin, Adam P., Pachter, Lior
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131376/
https://ncbi.nlm.nih.gov/pubmed/21642536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106541108
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