Interactions between Glucocorticoid Treatment and Cis-Regulatory Polymorphisms Contribute to Cellular Response Phenotypes

Glucocorticoids (GCs) mediate physiological responses to environmental stress and are commonly used as pharmaceuticals. GCs act primarily through the GC receptor (GR, a transcription factor). Despite their clear biomedical importance, little is known about the genetic architecture of variation in GC...

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Detalhes bibliográficos
Main Authors: Maranville, Joseph C., Luca, Francesca, Richards, Allison L., Wen, Xiaoquan, Witonsky, David B., Baxter, Shaneen, Stephens, Matthew, Di Rienzo, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131293/
https://ncbi.nlm.nih.gov/pubmed/21750684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002162
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