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A novel fusogenic herpes simplex virus for oncolytic virotherapy of squamous cell carcinoma
BACKGROUND: R849 is a neurovirulent γ(1)34.5 gene-deficient form of herpes simplex virus type 1 (HSV-1) and has LacZ genes at the deleted sites of the γ(1)34.5 gene. HF is a spontaneously occurring, fusogenic HSV-1 strain. The purpose of this work was to generate a virus that has the syncytial chara...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131258/ https://ncbi.nlm.nih.gov/pubmed/21663640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-294 |
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