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Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression

BACKGROUND: LIM kinase 1 (LIMK1) is expressed in both cytoplasmic and nuclear compartments, and is a key regulator of cytoskeletal organization involved in cell migration and proliferation. LIMK1 levels are increased in several human cancers, with LIMK1 over-expression in prostate and breast cancer...

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Autors principals: McConnell, Brice V, Koto, Karen, Gutierrez-Hartmann, Arthur
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131252/
https://ncbi.nlm.nih.gov/pubmed/21682918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-75
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