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Particle size reduction to the nanometer range: a promising approach to improve buccal absorption of poorly water-soluble drugs

Poorly water-soluble drugs, such as phenylephrine, offer challenging problems for buccal drug delivery. In order to overcome these problems, particle size reduction (to the nanometer range) and cyclodextrin complexation were investigated for permeability enhancement. The apparent solubility in water...

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Bibliografske podrobnosti
Main Authors: Rao, Shasha, Song, Yunmei, Peddie, Frank, Evans, Allan M
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131191/
https://ncbi.nlm.nih.gov/pubmed/21753876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S19151
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