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Improvement of colchicine oral bioavailability by incorporating eugenol in the nanoemulsion as an oil excipient and enhancer

The effect of eugenol on colchicine transport across an isolated rat intestinal membrane was studied using an in vitro diffusion chamber system. We found that eugenol increased the absorptive transport of the drug efficiently. The effect of eugenol on intestinal absorption of colchicine in an oral a...

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Autors principals: Shen, Qi, Wang, Ying, Zhang, Yi
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131190/
https://ncbi.nlm.nih.gov/pubmed/21753875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S20903
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