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Pathogenesis of Chagas' Disease: Parasite Persistence and Autoimmunity

Summary: Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast DNA (kDNA) minicircle to the genome of chagasic patients can explain the pathogenesis of the disease; in cases...

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Bibliografski detalji
Glavni autori: Teixeira, Antonio R. L., Hecht, Mariana M., Guimaro, Maria C., Sousa, Alessandro O., Nitz, Nadjar
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131057/
https://ncbi.nlm.nih.gov/pubmed/21734249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.00063-10
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