Increased availability of angiotensin AT(1) receptors leads to sustained arterial constriction to angiotensin II in diabetes – role for Rho-kinase activation

BACKGROUND AND PURPOSE: Antagonists of angiotensin AT(1) receptors elicit beneficial vascular effects in diabetes mellitus. We hypothesized that diabetes induces sustained availability of AT(1) receptors, causing enhanced arterial constriction to angiotensin II. EXPERIMENTAL APPROACH: To assess func...

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Bibliografski detalji
Glavni autori: Bagi, Zsolt, Feher, Attila, Cassuto, James, Akula, Komala, Labinskyy, Nazar, Kaley, Gabor, Koller, Akos
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2011
Teme:
Research Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130951/
https://ncbi.nlm.nih.gov/pubmed/21385178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01307.x
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