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Barriers to Non-Viral Vector-Mediated Gene Delivery in the Nervous System

Efficient methods for cell line transfection are well described, but, for primary neurons, a high-yield method different from those relying on viral vectors is lacking. Viral transfection has several drawbacks, such as the complexity of vector preparation, safety concerns, and the generation of immu...

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Detalhes bibliográficos
Main Authors: Pérez-Martínez, Francisco C., Guerra, Javier, Posadas, Inmaculada, Ceña, Valentín
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130907/
https://ncbi.nlm.nih.gov/pubmed/21225319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0364-7
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