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Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response

Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. When telomeres critically shorten, cells become susceptible to senescence and apoptosis. Telomerase, a cellular ribonucleoprotein enzyme, rebuilds the length of telomeres and promotes cellular viability. Leu...

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Autors principals: Wolkowitz, OM, Mellon, SH, Epel, ES, Lin, J, Reus, VI, Rosser, R, Burke, H, Compagnone, M, Nelson, JC, Dhabhar, FS, Blackburn, EH
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130817/
https://ncbi.nlm.nih.gov/pubmed/21242992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2010.133
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