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Small Compound 6-O-Angeloylplenolin Induces Mitotic Arrest and Exhibits Therapeutic Potentials in Multiple Myeloma

BACKGROUND: Multiple myeloma (MM) is a disease of cell cycle dysregulation while cell cycle modulation can be a target for MM therapy. In this study we investigated the effects and mechanisms of action of a sesquiterpene lactone 6-O-angeloylplenolin (6-OAP) on MM cells. METHODOLOGY/PRINCIPAL FINDING...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Liu, Ying, Chen, Xiao-Qin, Liang, Heng-Xing, Zhang, Feng-Xiang, Zhang, Bo, Jin, Jie, Chen, Yong-Long, Cheng, Yong-Xian, Zhou, Guang-Biao
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130785/
https://ncbi.nlm.nih.gov/pubmed/21755010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021930
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