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In vitro and in vivo activity of polyclonal and monoclonal human immunoglobulins G, M, and A against Pseudomonas aeruginosa lipopolysaccharide.

We evaluated the in vitro opsonophagocytic killing activity of monoclonal human immunoglobulin G (IgG), IgM, and IgA specific for Pseudomonas aeruginosa lipopolysaccharide and the in vivo protective capacity in neutropenic mice of both monoclonal and purified polyclonal IgG, IgM, and IgA. Monoclonal...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Pier, G B, Thomas, D, Small, G, Siadak, A, Zweerink, H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2491835/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.1.174-179.1989
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