Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics

Mammalian cells can decode the concentration of extracellular transforming growth factor-β (TGF-β) and transduce this cue into appropriate cell fate decisions. How variable TGF-β ligand doses quantitatively control intracellular signaling dynamics and how continuous ligand doses are translated into...

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Detalhes bibliográficos
Main Authors: Zi, Zhike, Feng, Zipei, Chapnick, Douglas A, Dahl, Markus, Deng, Difan, Klipp, Edda, Moustakas, Aristidis, Liu, Xuedong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130555/
https://ncbi.nlm.nih.gov/pubmed/21613981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.22
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