Metabolic factors, adipose tissue and plasminogen activator inhibitor-1 levels in type 2 diabetes: Findings from the Look AHEAD Study

OBJECTIVE: Plasminogen activator inhibitor-1 (PAI-1) production by adipose tissue is increased in obesity and its circulating levels are high in type 2 diabetes. PAI-1 increases cardiovascular risk by favoring clot stability and/or interfering with vascular remodeling. We investigated in obese diabe...

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Detalhes bibliográficos
Main Authors: Belalcazar, L. Maria, Ballantyne, Christie M., Lang, Wei, Haffner, Steven M., Rushing, Julia, Schwenke, Dawn C., Pi-Sunyer, F. Xavier, Tracy, Russell P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130500/
https://ncbi.nlm.nih.gov/pubmed/21512162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.224386
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