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A Random Sequencing Approach for the Analysis of the Trypanosoma cruzi Genome: General Structure, Large Gene and Repetitive DNA Families, and Gene Discovery

A random sequence survey of the genome of Trypanosoma cruzi, the agent of Chagas disease, was performed and 11,459 genomic sequences were obtained, resulting in ∼4.3 Mb of readable sequences or ∼10% of the parasite haploid genome. The estimated total GC content was 50.9%, with a high representation...

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Bibliografiske detaljer
Main Authors: Agüero, Fernán, Verdún, Ramiro E., Frasch, Alberto Carlos C., Sánchez, Daniel O.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC313047/
https://ncbi.nlm.nih.gov/pubmed/11116094
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