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Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants

DNA methylation, an essential regulator of transcription and chromatin structure, is established and maintained by the coordinated action of three DNA methyltransferases: DNMT1, DNMT3A and DNMT3B, and the inactive accessory factor DNMT3L. Disruptions in DNMT3B function are linked to carcinogenesis a...

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Detalhes bibliográficos
Main Authors: Van Emburgh, Beth O., Robertson, Keith D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130282/
https://ncbi.nlm.nih.gov/pubmed/21378119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr116
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