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Identification of altered function alleles that affect Bacillus subtilis PerR metal ion selectivity
Bacillus subtilis PerR is a Fur family repressor that senses hydrogen peroxide by metal-catalyzed oxidation. PerR contains a structural Zn(II) ion (Site 1) and a regulatory metal binding site (Site 2) that, upon association with either Mn(II) or Fe(II), allosterically activates DNA binding. In addit...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130269/ https://ncbi.nlm.nih.gov/pubmed/21398634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr095 |
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