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Evidence for a role of Hsp 70 in the regulation of the heat shock response in mammalian cells

Heat and other environmental insults (stress) cause unfolding of proteins, triggering the activation of heat shock transcription factor HSF (HSF 1 in vertebrates) that, in higher eukaryotes, involves trimerization of the factor and acquisition of heat shock element (HSE) DNA-binding ability. Interac...

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Autori principali: Baler, Ruben, Zou, Jianying, Voellmy, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Stress Society International 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC313015/
https://ncbi.nlm.nih.gov/pubmed/9222587
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