Loss of PTB or Negative Regulation of Notch mRNA Reveals Distinct Zones of Notch and Actin Protein Accumulation in Drosophila Embryo

Polypyrimidine Tract Binding (PTB) protein is a regulator of mRNA processing and translation. Genetic screens and studies of wing and bristle development during the post-embryonic stages of Drosophila suggest that it is a negative regulator of the Notch pathway. How PTB regulates the Notch pathway i...

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Detalhes bibliográficos
Main Authors: Wesley, Cedric S., Guo, Heng, Chaudhry, Kanita A., Thali, Markus J., Yin, Jerry C., Clason, Todd, Wesley, Umadevi V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130057/
https://ncbi.nlm.nih.gov/pubmed/21750738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021876
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