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Colitis decreases mechanosensitive K(2P) channel expression and function in mouse colon sensory neurons

TREK-1, TREK-2 and TRAAK are mechanosensitive two-pore domain K(+) (K(2P)) channels thought to be involved in the attenuation of mechanotransduction. Because colon inflammation is associated with colon mechanohypersensitivity, we hypothesized that the role of these channels in colon sensory (dorsal...

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Bibliografische gegevens
Hoofdauteurs: La, Jun-Ho, Gebhart, G. F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129930/
https://ncbi.nlm.nih.gov/pubmed/21512155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00417.2010
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