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Characterization of a Hormone Dependent Module Regulating Energy Balance
Under fasting conditions, metazoans maintain energy balance by shifting from glucose to fat burning. In the fasted state, SIRT1 promotes catabolic gene expression by deacetylating the forkhead factor FOXO in response to stress and nutrient deprivation. The mechanisms by which hormonal signals regula...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129781/ https://ncbi.nlm.nih.gov/pubmed/21565616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.04.013 |
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