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Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase

The oxidative catabolism of uric acid produces 5-hydroxyisourate (HIU), which is further degraded to (S)-allantoin by two enzymes, HIU hydrolase and 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) decarboxylase. The intermediates of the latter two reactions, HIU and OHCU, are unstable in soluti...

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Detalhes bibliográficos
Main Authors: French, Jarrod B., Neau, David B., Ealick, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129624/
https://ncbi.nlm.nih.gov/pubmed/21616082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.016
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