Successful Implantation of Bioengineered, Intrinsically Innervated, Human Internal Anal Sphincter

BACKGROUND & AIMS: To restore fecal continence, the weakened pressure of the internal anal sphincter (IAS) must be increased. We bioengineered intrinsically innervated human IAS, to emulate sphincteric physiology, in vitro. METHODS: We co-cultured human IAS circular smooth muscle with immortomou...

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Hlavní autoři: Raghavan, Shreya, Gilmont, Robert R., Miyasaka, Eiichi A., Somara, Sita, Srinivasan, Shanthi, Teitelbaum, Daniel H, Bitar, Khalil N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129458/
https://ncbi.nlm.nih.gov/pubmed/21463628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.03.056
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