Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis

Galectin-1 (Gal-1), a carbohydrate-binding protein whose secretion is enhanced by hypoxia, promotes tumor aggressiveness by promoting angiogenesis and T cell apoptosis. However, the importance of tumor versus host Gal-1 in tumor progression is undefined. Here we offer evidence that implicates tumor...

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Bibliographic Details
Main Authors:	Banh, Alice, Zhang, Jing, Cao, Hongbin, Bouley, Donna M, Kwok, Shirley, Kong, Christina, Giaccia, Amato J., Koong, Albert C., Le, Quynh-Thu
Format:	Artigo
Language:	Inglês
Published:	2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3129397/ https://ncbi.nlm.nih.gov/pubmed/21546572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4157
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Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis

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