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Loss of NRF2 impairs gastric nitrergic stimulation and function

Emerging research suggests that antioxidant gene expression has the potential to suppress the development of gastroparesis. However, direct genetic evidence that definitively supports this concept is lacking. We used mice carrying a targeted disruption of Nfe2l2, the gene that encodes the transcript...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mukhopadhyay, Sutapa, Sekhar, Konjeti R., Hale, Ashley B., Channon, Keith M., Farrugia, Gianrico, Freeman, Michael L., Gangula, Pandu R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129370/
https://ncbi.nlm.nih.gov/pubmed/21605664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.04.044
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