Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex

The human major histocompatibility complex (MHC) on chromosome 6p21 is a paradigm for genomics, showing remarkable polymorphism and striking association with immune and non-immune diseases. The complex genomic landscape of the MHC, notably strong linkage disequilibrium, has made resolving causal var...

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Main Authors: Vandiedonck, Claire, Taylor, Martin S., Lockstone, Helen E., Plant, Katharine, Taylor, Jennifer M., Durrant, Caroline, Broxholme, John, Fairfax, Benjamin P., Knight, Julian C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129247/
https://ncbi.nlm.nih.gov/pubmed/21628452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.116681.110
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