R-Ras and Rac GTPase Cross-talk Regulates Hematopoietic Progenitor Cell Migration, Homing, and Mobilization

Adult hematopoietic progenitor cells (HPCs) are maintained by highly coordinated signals in the bone marrow. The molecular mechanisms linking intracellular signaling network of HPCs with their microenvironment remain poorly defined. The Rho family GTPase Rac1/Rac2 has previously been implicated in c...

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Bibliographic Details
Main Authors: Shang, Xun, Cancelas, Jose A., Li, Lina, Guo, Fukun, Liu, Wei, Johnson, James F., Ficker, Ashley, Daria, Deidre, Geiger, Hartmut, Ratner, Nancy, Zheng, Yi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129188/
https://ncbi.nlm.nih.gov/pubmed/21572048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226951
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