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Detrimental effects of anti-apoptotic treatments in spinal cord injury

Long term functional impairments due to spinal cord injury (SCI) in the rat result from secondary apoptotic death regulated, in part, by SCI-induced decreases in protein levels of the anti-apoptotic protein Bcl-x(L). We have shown that exogenous administration of Bcl-x(L) spares neurons 24h after SC...

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Detalhes bibliográficos
Main Authors: Cittelly, Diana M, Nesic, Olivera, Johnson, Kathia, Hulsebosch, Claire, Perez-Polo, J. Regino
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128999/
https://ncbi.nlm.nih.gov/pubmed/18302959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.03.001
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