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Myc overexpression brings out unexpected antiapoptotic effects of miR-34a
Downregulation of microRNA-34a by Myc is known to be essential for tumorigenesis and improve tumor-cell survival. Conversely, upregulation of miR-34a by p53 is thought to enhance its acetylation and activity and contribute to the pro-apoptotic effects of this tumor suppressor. We sought to determine...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128883/ https://ncbi.nlm.nih.gov/pubmed/21297663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.634 |
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