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An Emerging Model for BAP1’s Role in Regulating Cell Cycle Progression
BRCA1-associated protein-1 (BAP1) is a 729 residue, nuclear-localized deubiquitinating enzyme (DUB) that displays tumor suppressor properties in the BAP1-null NCI-H226 lung carcinoma cell line. Studies that have altered BAP1 cellular levels or enzymatic activity have reported defects in cell cycle p...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128820/ https://ncbi.nlm.nih.gov/pubmed/21484256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-011-9184-6 |
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