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Human Adipose-Derived Stromal Cells Stimulate Autogenous Skeletal Repair via Paracrine Hedgehog Signaling with Calvarial Osteoblasts

Human adipose-derived stromal cells (hASCs) have the proven capacity to ossify skeletal defects. The mechanisms whereby hASCs stimulate bone repair are not fully understood. In this study, we examined the potential for hASCs to stimulate autogenous repair of a mouse calvarial defect. Immunofluoresen...

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Autors principals: Levi, Benjamin, James, Aaron W., Nelson, Emily R., Li, Shuli, Peng, Michelle, Commons, George W., Lee, Min, Wu, Benjamin, Longaker, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128781/
https://ncbi.nlm.nih.gov/pubmed/20698749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2010.0250
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