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Aryl Hydrocarbon Receptor-Null Allele Mice Have Hematopoietic Stem/Progenitor Cells with Abnormal Characteristics and Functions

The aryl hydrocarbon receptor (AhR) belongs to the basic helix-loop-helix family of DNA-binding proteins that play a role in the toxicity and carcinogenicity of certain chemicals. The most potent ligand of the AhR known is 2,3,7,8-tetracholorodibenzo-p-dioxin. We previously reported tetrachlorodiben...

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Autors principals: Singh, Kameshwar P., Garrett, Russell W., Casado, Fanny L., Gasiewicz, Thomas A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128774/
https://ncbi.nlm.nih.gov/pubmed/20874460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2010.0333
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